Argireline microneedling: Natural botox to flawless skin


Updated: 19 May 2024

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Argireline microneedling: Natural botox to flawless skin

Argireline microneedling or botox micro-needling helps reduce worry lines or forehead wrinkles prominently. It is available in various forms but the most effective is “Argireline-Solution”. This solution can be incorporated into the skin via a derma roller or microneedling pen and has various benefits. Argireline peptide is an amazing substance that can control wrinkles on the face and is like a baby Botox.

Using Argireline for skin tightening after micro needling: Botox in a bottle

Many people believe that having a youthful and attractive face is a sign of good health and success. There are various ways to achieve this, including facial surgery, Botox injections, dermal fillers, and using cosmetic products. The choice of procedure depends on factors like age, personal preferences, and budget, with the level of invasiveness being an important consideration. Let’s explore Argireline, what it is, and how it can be used in skincare.

Microneedling boosts collagen production in the skin. Using Argireline serum during or after microneedling makes the whole process way more effective. You can get tight and illuminated skin with this combo and can get enormous advantages. The procedure is simple

1- Apply numbing cream and keep it on the skin for 10-15mins

2- Wipe it off with a gentle piece of cloth or with a wet tissue but do not rub

3- Apply Argireline serum on the face and use a micro-needling pen or derma roller on the face with a gliding effect

4- Apply Moisturiser

5- You will observe a downtime of 12-24hrs and your skin will look amazingly good

6- Do not forget to use sunscreen regularly

7- Apply Argireline serum daily for at least 3 months for visible results

Argireline microneedling as an alternative to Botox

Argireline, or Acetyl Hexapeptide-8, is a safe cosmetic ingredient that works like Botox to reduce facial lines and wrinkles. It’s less invasive than chemical peels or laser treatments. It is a peptide and restricts the ability of muscles to contract. Its muscle-to-nerve communication is so strong that it watches out the wrinkles around the eyes and on the face.

Argireline is not an alternative to Botulinum toxin as it resides on the upper layer of the skin and its deeper penetration into the skin is limited. On the other hand, Botulinum toxin lasts for months and years with systematic distribution of the toxin. Argireline for skin is considered less toxic and cheaper as compared to neurotoxin botulinum toxin. The results are not the same, but rather temporary with Arginine and more reliable with Botox. Another reason that prevents users from getting Botox is the side effects like

  • Dry mouth
  • Anaphylactic shock
  • Facial muscle paralysis
  • Difficult swallowing because of stiff facial muscles

It is essential to understand the mechanism of action of Argireline and Botox to fully understand the science behind it. Argireline is only effective mildly if it comes with a water to oil-based formulation as it resides on the dermis, but if it comes with oil to water-based formulation it is useless.

Using Argireline with other products

Argireline and retinol

Retinol is used widely as an anti-aging product and fights signs of ageing very effectively. It is very important to provide your skin with a proper shield against the sun while using retinol. Moreover, the skin gets extra dry and flaky and it is recommended to use retinol at night. Argireline, on the other hand, have no such limitations or restriction and is quite safe to use. Using Retinol and Argirenine is not recommended.

Argireline and hydroquinone

Hydroquinone is very effective in treatment of hyperpigmentation and show maximum results if applied on skin in combination with tretinoin. The skincare routine with hydroquinone is effective if used at night with proper cleansing and sun-protection. Using Argireline and hydroquinone together is also not recommended.

Argireline and hyaluronic acid

Using Argireline and hyaluronic acid in your skincare routine is an amazing regime for maintaining moisture in the skin. Argireline and hyaluronic acid together can build new bonds in the skin removing dead cells and giving you flawless skin.

Argireline microneedling benefits in skincare

The benefits are multiple in skincare

  • Anti-aging
  • plumped skin
  • Botox free still gives you botox like effect
  • Increases collagen turnover
  • Replaces dead cells
  • Effective for forehead and eye area wrinkles

Core benefit:

The major benefit is limiting the muscle movement responsible for wrinkles on the face and maintaining hydration in the skin. 5 types of wrinkles that can be treated via Argireline microneedling or using Argireline after microneedling.

  • Wrinkles under eyes
  • Wrinkles around eyes
  • Wrinkles on forehead
  • Wrinkles around smile
  • Wrinkles on jowls

Argireline usage

It is safe to use, but honestly speaking it also depends upon the complete formulation you are using. The patent product belongs to Germany, and other brands use it in their skincare formulation. A clean face maximizes the effect of any product when applied to the skin.

Some important tips before you incorporate Argireline in your skincare

Argireline is available in different concentrations, it is recommended to start with the lowest concentration to avoid any allergic or skin reaction. However, Argireline is safe to use and does not harm the skin in any way. Moreover, it is highly recommended to use the formulation having hyaluronic acid along with Argireline to get maximum hydration.

Getting additional benefits from Argireline

Microneedling is a proven and effective method to get flawless skin. Using Argireline after microneedling can tighten the skin and make you look younger. The benefits you get via the Argireline-Microneedling combo involve

  • Flexible and elastic skin
  • Even skin tone
  • Removal of deal cells
  • wrinkle free face
  • Crow feet around eyes vanishes

Available products in the market containing Argireline

No doubt Argireline serum benefits are multiple but, Argireline alone cannot make your skin look flawless, it is essential to incorporate other agents into the skin. There are several serums available in the market having Argireline but ”The Ordinary” is our top pick. TO “The ordinary Argireline solution 10%” is the authentic and licensed product containing Argireline.

The ingredients in the product involve

  • Water
  • Propanediol
  • Acetyl Hexapeptide-8,
  • Trisodium Ethylenediamine Disuccinate
  • Gellan Gum
  • Sodium Chloride
  • Isoceteth-20, Dimethyl Isosorbide,
  • Potassium Sorbate
  • Phenoxyethanol
  • Chlorphenesin

Review of “The ordinary Argireline solution”

Most of the customers claim that they have noticed a significant reduction in their forehead lines after using it for at least 3 months. It is also known as baby Botox in a bottle.

Overall score:

Based upon the genuine customer reviews we give it 3.5/5

Final words

The downside is that you need to use anti-wrinkle creams containing Argireline daily for prominent results. Many studies support the effectiveness of Argireline in reducing wrinkles, and it’s considered safe in cosmetics at concentrations up to 0.005%. However, more research is needed to determine the safety of higher concentrations and long-term use. We’ve studied the stability of Argireline in cosmetic formulations and found that while the deacetylated form was not detected, the oxidized form was present in creams and serums. This oxidation may occur due to exposure to air or certain ingredients in the cream acting as oxidants.


Saba Saeed

Saba Saeed

Saba Saeed M.phil in pharmaceutical sciences., is a Board-Certified pharmacist with research expertise in Dermatology, Fellow of the American research centre in drug development and discovery, and has been an international leader in developing microneedles for different skin conditions for over 15 years. She played an important role in developing insulin loaded microneedles and later proved effectiveness of micro-needling technique in various cosmetic and dermatology treatments. She pioneered an online consultation center regarding effectiveness of microneedling and dosage of various substances delivered via it. She provided online consultation to a number of men and women which helped them in making right decision for their skin.She also worked on novel drug delivery system i.e. mucoadhesive buccal patches for delivery of drugs with narrow therapeutic index. She is recently working on 3D-printing of drugs and loading of anti-diabetic drugs on microneedles with Dr. Sohail Muhammad Arshad (Dean Faculty of Pharmacy). She has contirbuted alot in serving needs of the community and is uplifting culture of safety and security. She provides online consultation on various health related concerns and you can book an appointment directly with her to inquire about related concerns.She also worked on novel drug delivery system i.e. mucoadhesive buccal patches for delivery of drugs with narrow therapeutic index. She is recently working on 3D-printing of drugs and loading of anti-diabetic drugs on microneedles with Dr. Sohail Muhammad Arshad (Dean Faculty of Pharmacy).She has contirbuted alot in serving needs oft he community and is uplifting culture of safety and security. She provides online consultation on various health related concerns and you can book an appointment directly with her to inquire about related concerns.

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